Consideraciones en el estudio anatómico sobre el músculo peroneo tercero, peroneo anterior, tercer peroneo, peroneo tertius, fibularis tertius

The anatomy of the foot, their knowledge, opens up a wide range of expectations so accurate for diagnosing various pathologies of the foot, and above all, to know you better. The purpose of this study was to look closely at the anatomy of the muscle Tertius peroneo to define its origin and insercción to the controversy raised by the literature, its function in the foot, and its frequency, it is a muscle that is not present in all feet. The third peroneo muscle, also known as peroneo Tertius, is a muscle group of the previous leg, which in the current literature is considered inconsistent, that character was not found in our study. We repeat that the authors describe as an inconstant muscle (eg. Rouvière) adjective meaning in anatomy that it is a muscle in less than 45% of cases. For Testud, in the absence black 14 times in 100, the Europeans 7 or 8 times 100, and lacking in monkeys. According to Kapandji is dorsal flexor, abductor and pronator foot. We intend to demonstrate our dissections, a muscle that is most of what appears and where is its origin and insertion, as well as its presentation and position by photographs of cadaver feet.La anatomía del pie, su conocimiento, nos abre un amplio abanico de expectativas para diagnosticar de manera certera diversas patologías del pie, y sobre todo, para conocerlo mejor. El objeto de éste estudio fue observar detenidamente la anatomía del músculo peroneo tertius, definir su origen e insercción ante la controversia que suscita la bibliografía consultada, su función en el pie, y su frecuencia de aparición, pues es un músculo que no está presente en todos los pies. El músculo tercer peroneo, conocido también como peroneo tertius, es un músculo del grupo anterior de la pierna, que en la literatura actual es considerado inconstante, carácter que no fue comprobado en nuestro estudio. Repetimos que diferentes autores lo califican como un músculo inconstante (por ej. Rouviére), significando éste adjetivo en anatomía que es un músculo presente en menos del 45% de los casos. Para Testud, en la raza negra falta 14 veces en 100, en los europeos 7 u 8 veces cada 100, y falta en los monos. Según Kapandji es flexor dorsal, abductor y pronador del pie. Pretendemos demostrar con nuestras disecciones, que es un músculo más habitual de lo que parece y dónde está su origen e inserción, así como su función,presentación y posición mediante fotografías en pies de cadáver

A method to quantify the reduction of back and hip muscle fatigue of lift-support exoskeletons

Cumulative back muscle fatigue plays a role in the occurrence of low-back injuries in occupations that require repetitive lifting of heavy loads and working in forward leaning postures. Lift-support exoskeletons have the potential to reduce back and hip muscle activity, thereby delaying the onset of fatigue in these muscles. Therefore, exoskeletons are being considered a potentially important tool to further reduce workload-related injuries. However, today no standards have been established on how to benchmark the support level of lift-support exoskeletons. This work proposes an experimental protocol to quantify the support level of a lift-support exoskeletons on instant changes in muscle activity and fatigue development while maintaining a static forward leaning posture. It then applies the protocol to experimentally assess the effect of the support provided by a commercially available lift-support exoskeleton, the LiftSuit 2.0 (Auxivo AG, Schwerzenbach, Switzerland), on the user. In a sample of 14 participants, the amplitude of the muscle activity of the back muscles and hip muscles was significantly reduced. Wearing the exoskeleton significantly reduced the amount of fatigue developed during the task . Changes in muscle fatigue can be objectively recorded and correlated with relevant changes for exoskeleton users: the time a task can be performed and perceived low-back fatigue. Thus, including such measures of fatigue in standardized benchmarking procedures will help quantify the benefits of exoskeletons for occupational use

Characterization of Antimicrobial Susceptibility of Bacterial Biofilms on Biological Tissues

abstract: Prosthetic joint infection (PJI) is a devastating complication associated with total joint arthroplasty that results in high cost and patient morbidity. There are approximately 50,000 PJIs per year in the US, imposing a burden of about $5 billion on the healthcare system. PJI is especially difficult to treat because of the presence of bacteria in biofilm, often highly tolerant to antimicrobials. Treatment of PJI requires surgical debridement of infected tissues, and local, sustained delivery of antimicrobials at high concentrations to eradicate residual biofilm bacteria. However, the antimicrobial concentrations required to eradicate biofilm bacteria grown in vivo or on tissue surfaces have not been measured. In this study, an experimental rabbit femur infection model was established by introducing a variety of pathogens representative of those found in PJIs [Staphylococcus Aureus (ATCC 49230, ATCC BAA-1556, ATCC BAA-1680), Staphylococcus Epidermidis (ATCC 35984, ATCC 12228), Enterococcus Faecalis (ATCC 29212), Pseudomonas Aeruginosa (ATCC 27853), Escherichia Coli (ATCC 25922)]. Biofilms of the same pathogens were grown in vitro on biologic surfaces (bone and muscle). The ex vivo and in vitro tissue minimum biofilm eradication concentration (MBEC; the level required to eradicate biofilm bacteria) and minimum inhibitory concentration (MIC; the level required to inhibit planktonic, non-biofilm bacteria) were measured using microbiological susceptibility assays against tobramycin (TOB) and vancomycin (VANC) alone or in 1:1 weight combination of both (TOB+VANC) over three exposure durations (6 hour, 24 hour, 72 hour). MBECs for all treatment combinations (pathogen, antimicrobial used, exposure time, and tissue) were compared against the corresponding MIC values to compare the relative susceptibility increase due to biofilm formation. Our data showed median in vitro MBEC to be 100-1000 times greater than the median MIC demonstrating the administration of local antimicrobial doses at MIC level would not kill the persisting bacteria in biofilm. Also, administering dual agent (TOB+VANC) showed median MBEC values to be comparable or lower than the single agents (TOB or VANC)Dissertation/ThesisMasters Thesis Bioengineering 201

An overview of offshore wind energy resources in Europe under present and future climate

Long-term sustainable development of European offshore wind energy requires knowledge of the best places for installing offshore wind farms. To achieve this, a good knowledge of wind resources is needed, as well as knowledge of international, European, and national regulations regarding conflict management, marine environment conservation, biodiversity protection, licensing processes, and support regimes. Such a multidisciplinary approach could help to identify areas where wind resources are abundant and where conflicts with other interests are scarce, support measures are greater, and licensing processes are streamlined. An overview of offshore wind power studies at present, and of their future projections for the 21st century, allows for determining the optimal European locations to install or maintain offshore wind farms. Only northern Europe, the northwest portion of the Iberian Peninsula, the Gulf of Lyon, the Strait of Gibraltar, and the northwest coast of Turkey show no change or increase in wind power, revealing these locations as the most suitable for installing and maintaining offshore wind farms in the future. The installation of wind farms is subject to restrictions established under international law, European law, and the domestic legal framework of each EU member state. Europe is moving toward streamlining of licensing procedures, reducing subsidies, and implementing auction systems.Xunta de Galicia | Ref. ED431C 2017/64Xunta de Galicia | Ref. ED481A-2016/36Fundação para a Ciência e a Tecnologia | Ref. SFRH/BPD/118142/20

Impact of the quality of life related to foot health in a sample of pregnant women : a case control study

5 p.Pregnancy women coincide with numerous anatomical and physiological changes, which are believed to have a harmful effect on the quality of life related to foot health. The goal of this research was to identify and compare the impact foot health and overall health in a sample of pregnancy women and women without pregnancies with normalised reference values. A sample of 159 participants of a mean age of 30.13±6.28 came to the area of midwifery center where self-reported data were registered, informants’ with a 1 or various pregnancy was determined and the scores obtained were compared in the foot health status questionnaire (FHSQ). This has 13 questions that assess 4 health domains of the feet, namely pain, function, general health, and footwear. The pregnant women group showed a worse quality of life related to health in general and to foot health specifically at the following domains, foot function, footwear, general foot, health, physical activity, social capacity, and vigor (P<0.05) and there were no differences at foot pain and general health (P>0.05). Pregnant women present a negative impact on the quality of life related to foot health, which appears to be associated with the pregnancy period.S

The habits of physical activity of the older women in Spain

Dada la inexistencia de estudios precedentes de hábitos de actividad física en el conjunto de mujeres mayores de 65 años en España, la investigación persigue comprobar las posibles desigualdades y diferencias en la práctica de actividad física semanal de las mujeres mayores con respecto a los hombres. La metodología cuantitativa empleada ha consistido en la aplicación de un cuestionario estructurado a una muestra aleatoria de las mujeres y varones mayores de 65 años en España. Las conclusiones obtenidas revelan que en este grupo socio demográfico de las personas mayores de 65 años, y a diferencia de los otros grupos con menor edad, un mayor porcentaje de mujeres que de varones realiza actividad física semanal (sin incluir el pasear). Esta desigualdad viene acompañada y quizás explicada por una serie de diferencias en la relación con la práctica de actividad física por parte de las mujeres mayores en comparación a gran parte de los hombres mayores, y que quizás configuren lo que podría denominarse como una cultura deportiva femenina de las mujeres mayores: tanto en las actividades practicadas, como en el espacio utilizado, el modo de organización de la actividad, y en el modo de acudir a la actividad

Skin Bioimpedance Analysis to Determine Cellular Integrity by Phase Angle in Women with Fibromyalgia: A Cross-Sectional Study.

Oxidative stress has been proposed as a significant part of the pathogenesis of fibromyalgia, and the phase angle in bioelectrical impedance analysis has been explored as a potential technique to screen oxidative abnormalities. This study recruited 35 women with fibromyalgia and 35 healthy women, who underwent bioelectrical impedance analysis and maximum isometric handgrip strength tests. Women with fibromyalgia showed lower bilateral handgrip strength (right hand: 16.39 ± 5.87 vs. 27.53 ± 4.09, p < 0.001; left hand: 16.31 ± 5.51 vs. 27.61 ± 4.14, p < 0.001), as well as higher body fat mass (27.14 ± 10.21 vs. 19.94 ± 7.25, p = 0.002), body fat percentage (37.80 ± 8.32 vs. 30.63 ± 7.77, p < 0.001), and visceral fat area (136.76 ± 55.31 vs. 91.65 ± 42.04, p < 0.01) compared with healthy women. There was no statistically significant difference in muscle mass between groups, but women with fibromyalgia showed lower phase angles in all body regions when compared with healthy control women (right arm: 4.42 ± 0.51 vs. 4.97 ± 0.48, p < 0.01; left arm: 4.23 ± 0.48 vs. 4.78 ± 0.50, p < 0.001; trunk: 5.62 ± 0.77 vs. 6.78 ± 0.84, p < 0.001; right leg: 5.28 ± 0.56 vs. 5.81 ± 0.60, p < 0.001; left leg: 5.07 ± 0.51 vs. 5.69 ± 0.58, p < 0.001; whole body: 4.81 ± 0.47 vs. 5.39 ± 0.49, p < 0.001). Moreover, whole-body phase-angle reduction was only predicted by the presence of fibromyalgia (R 2 = 0.264; β = 0.639; F(1,68) = 24.411; p < 0.001). Our study revealed significantly lower phase angle values, lower handgrip strength, and higher fat levels in women with fibromyalgia compared to healthy controls, which are data of clinical relevance when dealing with such patients.post-print1,25 M

Sex difference in Frailty older adults with foot pain Spanish population: An observational study

Frailty is a condition that can increase the risk of falls. In addition, foot pain can influence older adults and a ect their frail condition. The main objective was to measure the frailty degree in older adults in a Spanish population with foot pain from moderate to severe. Method: This is a cross-sectional descriptive study. A sample of people older than 60 years (n = 52), including 26 males and 26 females, were recruited, and frailty disability was measured using the 5-Frailty scale and the Edmonton Frailty scale (EFS). Results: Spearman's correlation coe cients were categorized as weak (rs 0.40), moderate (0.41 rs 0.69), or strong (0.70 rs 1.00). There was a statistically significant correlation for the total score (p 0.05). In addition, females and males showed similar 5-Frailty and Edmonton Frail scales scores with no di erence (p > 0.05). Conclusion: Foot pain above 5 points, i.e., from moderate to severe, does not a ect the fragility more in one sex than another

Bmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell death.

Prolonged seizures (status epilepticus, SE) can cause neuronal death within brain regions such as the hippocampus. This may contribute to impairments in cognitive functioning and trigger or exacerbate epilepsy. Seizure-induced neuronal death is mediated, at least in part, by apoptosis-associated signaling pathways. Indeed, mice lacking certain members of the potently proapoptotic BH3-only subfamily of Bcl-2 proteins are protected against hippocampal damage caused by status epilepticus. The recently identified BH3-only protein Bcl-2-modifying factor (Bmf) normally interacts with the cytoskeleton, but upon certain cellular stresses, such as loss of extracellular matrix adhesion or energy crisis, Bmf relocalizes to mitochondria, where it can promote Bax activation and mitochondrial dysfunction. Although Bmf has been widely reported in the hematopoietic system to exert a proapoptotic effect, no studies have been undertaken in models of neurological disorders. To examine whether Bmf is important for seizure-induced neuronal death, we studied Bmf induction after prolonged seizures induced by intra-amygdala kainic acid (KA) in mice, and examined the effect of Bmf-deficiency on seizures and damage caused by SE. Seizures triggered an early (1-8 h) transcriptional activation and accumulation of Bax in the cell death-susceptible hippocampal CA3 subfield. Bmf mRNA was biphasically upregulated beginning at 1 h after SE and returning to normal by 8 h, while again being found elevated in the hippocampus of epileptic mice. Bmf upregulation was prevented by Compound C, an inhibitor of adenosine monophosphate-activated protein kinase, indicating Bmf expression may be induced in response to bioenergetic stress. Bmf-deficient mice showed normal sensitivity to the convulsant effects of KA, but, surprisingly, displayed significantly more neuronal death in the hippocampal CA1 and CA3 subfields after SE. These are the first studies investigating Bmf in a model of neurologic injury, and suggest that Bmf may protect neurons against seizure-induced neuronal death in vivo

POWERbreathe® Inspiratory Muscle Training in Amyotrophic Lateral Sclerosis.

Inspiratory muscle training may benefit respiratory function, cardiocirculatory parameters, quality of life and functionality in neuromuscular diseases. This pilot study aimed to demonstrate the POWERbreathe® inspiratory muscle training effects on maximum inspiratory pressure (PImax), heart rate (HR) and HR variability, as well as the quality of life impairment and functionality in patients with Amyotrophic Lateral Sclerosis (ALS). A pilot single-blinded, non-randomized controlled clinical trial was carried out. A total of 20T ALS patients were enrolled and divided into experimental (n = 10) and control (n = 10) groups. The experimental group received POWERbreathe® inspiratory muscle training in conjunction with usual care, and the control group received only usual care for 8 weeks. PImax (measured by POWERbreathe® KH1), HR and HR variability (evaluated by Polar H7), quality of life impairment [measured by the Amyotrophic Lateral Sclerosis Assessment Questionnaire—40 items (ALSAQ-40)] and functionality [assessed by the ALS Functional Rating Scale Revised (ALSFRS-R)] were collected at baseline and after 8 weeks of intervention. We detected statistically significant differences (p < 0.05) with an effect size ranging from medium to large (Cohen’s d = 0.72–1.37); relative to the control group, the experimental group had an increased PImax (mean difference = 10.80 cm H2O; 95% CI = 3.42–18.17) and ALSFRS-R score (mean difference = 5.30 points; 95% CI = −0.03–10.63) and reduced HR (mean difference = −8.80 beats-per-minute; 95% CI = −20.27–2.67) and R-R interval (mean difference = 78.30 ms; 95% CI = 2.89–153.70). POWERbreathe® inspiratory muscle training, in addition to usual care, may improve inspiratory strength and heart rate in patients with ALS. These results encourage larger and longer trials investigating potential clinically relevant benefits of inspiratory muscle training to these patients over the disease course.post-print6421 K